General News
Scientists Create Mice With Large Amounts of Human Brain Tissue
By Angel No Lie | KPD Online | 17 September 2026
Scientists develop part-human, part-mouse brain model
Scientists at Stanford University have created genetically engineered mice containing a large amount of lab-grown human brain tissue, in a breakthrough that could provide a new way to study neurological and psychiatric disorders.
The research, published in Nature on 16 September 2026, involves transplanting human cortical organoids—three-dimensional clusters of brain cells grown from human stem cells—into mice whose developing brains had been genetically altered so that much of the cerebral cortex and hippocampus would not form.
The resulting animals are known as xenocortical mice.
Despite headlines describing them as having “half-human brains,” the science is more specific: the animals remain mice, but much of the tissue occupying the space normally taken by the mouse cortex is derived from human cells. STAT notes that the “half-human” description refers to the brain tissue’s volume rather than meaning that half of the mouse’s neurons are human.
Potential medical applications
The researchers believe the model could eventually help scientists investigate conditions including:
- autism and other neurodevelopmental disorders
- epilepsy
- schizophrenia
- cerebral palsy
- intellectual disabilities
- neurodegenerative diseases
- rare disorders affecting human brain development
The advantage is that researchers can potentially observe human neurons developing and responding to physiological conditions inside a living organism.
The study also demonstrated the possibility of using the animals to examine how human neural tissue responds to injury.
A striking finding about oxygen deprivation
The research also provided evidence that human neurons inside the mice responded differently to a shortage of oxygen than the surrounding mouse tissue.
This matters because oxygen deprivation is involved in several neurological injuries and diseases.
The ability to examine human-derived neurons under such conditions in a living organism could eventually help researchers investigate why certain human brain cells are particularly vulnerable to injury.
The ethical questions
The experiment has also revived difficult questions about how far scientists should go when combining human cells with animals.
The central concern is whether increasingly sophisticated human neural tissue could eventually alter an animal’s cognitive abilities, perception or capacity to experience suffering.
The researchers anticipated these concerns.
According to the Nature paper, the project underwent review by Stanford’s stem-cell oversight committee and animal-care committee, with additional consultation involving bioethicists and an independent ethics committee. The researchers also conducted behavioral and cognitive testing to look for altered capabilities.
The authors themselves say that future experiments involving more mature human neural tissue will require continued ethical oversight.
They specifically identify questions surrounding more advanced cortical organization, mature neural networks and possible changes in animal capabilities.
What makes this experiment different?
Human brain organoids have previously been transplanted into rodents.
For example, earlier work from Stanford researchers demonstrated that human cortical organoids could integrate into developing rat brains and form functional connections.
The 2026 experiment goes substantially further.
Instead of placing a relatively small human graft alongside an intact rodent cortex, researchers removed the developmental competition for space by preventing much of the mouse cortex from forming in the first place.
This allowed the human-derived tissue to expand into most of the available cortical region. Nature describes this as a way of overcoming one of the major limitations of previous transplantation experiments.
Independent assessment
The breakthrough is significant because it addresses a longstanding problem in neuroscience: how to study human brain cells in a living system without experimenting directly on human brains.
However, the findings should not be interpreted as evidence that scientists have created an animal with a human mind. The experiment produced a mouse whose developing cortex contains a large amount of human-derived neural tissue that can form connections with the mouse nervous system.
The technology could eventually improve research into diseases that are difficult to reproduce using conventional mice. At the same time, the more human-like these experimental brains become, the more carefully researchers will need to assess animal welfare and cognitive consequences.
For now, the study represents an important step in human brain modeling, rather than the creation of a human-animal hybrid in the science-fiction sense.
Primary scientific source: Kaganovsky et al., Nature, “Developmental xenocortication using human-derived organoids in mice,” published 16 September 2026.
Additional reporting: Stanford Medicine, Nature, Reuters and Science News.
General News
Gold Rises Over 1% as Investors Digest Fed Hike, Oil Rally Stalls
By Angel No Lie | KPD Online | 17 September 2026 | Independent Markets Report
Gold prices moved higher on Thursday as investors assessed the U.S. Federal Reserve’s latest interest-rate decision, while easing concerns over Middle East oil supplies took some momentum out of the recent crude rally.
Spot gold was initially up more than 1% in Asian trading, reaching about $4,310.49 per ounce at 0149 GMT, according to Reuters. Later in the session, the gain had moderated to 0.8%, at $4,295.26, showing how quickly prices were adjusting after the Fed decision.
Oil rally loses momentum
The other major part of the market story is oil.
Brent crude futures fell 1.2% to $104.59 a barrel, while U.S. West Texas Intermediate declined 1.1% to $101.29 in early Thursday trading. Both contracts had fallen by roughly $3 on Wednesday.
The decline followed reports that Saudi Arabia was offering additional crude cargoes to Asian buyers through ship-to-ship transfers off Sohar, Oman.
The alternative export route is helping reduce immediate concerns about supply disruptions following attacks on Saudi Arabia’s East-West pipeline and disruption at the Red Sea export hub of Yanbu.
Commodity snapshot
| Asset | Latest reported move |
|---|---|
| Spot gold | $4,295.26/oz, +0.8% |
| Spot gold earlier | $4,310.49/oz, +1.1% |
| U.S. gold futures | $4,333.90/oz, -1.2% |
| Brent crude | $104.59/bbl, -1.2% |
| WTI crude | $101.29/bbl, -1.1% |
| Silver | $63.73/oz, +1.2% |
| Platinum | $1,783.56/oz, +1.7% |
| Palladium | $1,296.70/oz, +2.2% |
Figures reflect different points in Thursday’s trading and therefore should not be interpreted as simultaneous closing prices.
Why oil matters for gold
Oil and gold are responding to several of the same macroeconomic forces, but in different ways.
Higher oil prices can intensify inflation concerns because energy is an important input into transportation, manufacturing and household costs. Persistent energy inflation can, in turn, make central banks more reluctant to cut interest rates.
Conversely, a sustained decline in oil prices could reduce some inflation pressure. Reuters quoted OANDA analyst Kelvin Wong as saying continued oil weakness could provide additional support for gold over the medium term.
For now, however, the oil market remains exposed to developments in the Middle East. Reuters reported that the East-West pipeline disruption has not been fully resolved and that uncertainty remains over repairs.
The bigger picture
The market is therefore dealing with two competing forces.
For gold:
- renewed safe-haven demand;
- geopolitical uncertainty;
- expectations surrounding inflation;
- technical buying after the recent decline;
- but also pressure from relatively high U.S. interest rates.
For oil:
- continuing geopolitical and transportation risks;
- disruption affecting Saudi export infrastructure;
- alternative shipment arrangements through Oman;
- and signs that some immediate supply fears are easing.
Independent assessment
Thursday’s market action does not point to a single, straightforward trend.
Gold’s initial more-than-1% rise was significant, but the subsequent moderation shows that investors remain sensitive to the Fed’s higher-for-longer interest-rate signal. Meanwhile, oil’s retreat suggests that alternative Saudi export arrangements have reduced some of the immediate supply anxiety, although the underlying Middle East risks remain.
The key question for markets is whether oil prices continue to fall as supply routes normalize, or whether renewed disruptions push energy prices higher again. That outcome could materially influence inflation expectations, interest-rate expectations and, consequently, gold.
In short: gold is being supported by defensive and technical factors, while oil is losing some of its geopolitical risk premium—but neither move should yet be interpreted as a settled new market direction.
Sources: Reuters; U.S. Federal Reserve.
General News
Oil Prices Extend Losses as Middle East Supply Fears Ease
17 September 2026 | Energy & Markets
Oil prices fall for a second day
Oil prices extended their decline in Asian trading on Thursday as signs that Saudi Arabia can redirect some crude exports through Oman eased immediate concerns about shortages caused by disruptions to Middle Eastern supply routes.
Brent crude futures were down about 1.2% at $104.59 a barrel, while U.S. West Texas Intermediate (WTI) fell about 1.1% to $101.29 in early trading. Both benchmarks had dropped roughly $3 on Wednesday.
The decline represents a change in market sentiment after oil prices climbed sharply earlier in September as attacks on energy infrastructure and shipping routes raised concerns that Middle Eastern exports could be significantly curtailed.
What could happen next?
The direction of oil prices will depend heavily on whether alternative supply routes remain available and whether further attacks disrupt additional infrastructure.
For now, the market appears to be responding to evidence that Saudi Arabia can partially compensate for lost Red Sea exports.
However, this is not the same as a return to normal supply conditions.
The IEA has warned that disruptions in the Gulf and wider Middle East could keep global oil markets tight. The EIA’s September outlook also assumes that Middle Eastern oil flows will remain constrained through the fourth quarter of 2026, although it expects flows to gradually increase as shipping companies develop alternative routes.
That leaves the market particularly sensitive to three developments:
- Whether Saudi Arabia can sustain alternative shipments through Oman.
- How quickly the East-West pipeline can be repaired.
- Whether fighting around the Strait of Hormuz and Red Sea intensifies or eases.
Independent assessment
The latest decline in oil prices is primarily a supply-logistics story rather than evidence that the Middle East crisis has ended.
Saudi Arabia’s ability to redirect crude through Oman has reassured traders that at least some displaced barrels can still reach Asian buyers. Lower-than-expected U.S. inventory withdrawals have provided another bearish signal.
At the same time, oil remains above $100, tanker traffic through the Strait of Hormuz remains severely affected, Saudi production has been disrupted and diesel markets are experiencing extraordinary tightness.
The immediate supply panic has eased, but the underlying risk to global energy flows remains significant.
For consumers, refiners and governments, the key issue in the coming days will therefore be whether these alternative shipping arrangements develop into a sustained supply solution—or whether another disruption causes the risk premium in oil prices to rise again.
Sources
Reuters, Oil prices extend losses as fears of Middle East supply disruptions ease, 17 September 2026.
Reuters, Oil slips as Saudi Arabia offers more crude via Oman, 16 September 2026.
U.S. Energy Information Administration, Short-Term Energy Outlook, September 2026.
Reuters, reporting on Saudi supply, Asian diesel markets and Middle East disruptions.
General News
Palace Responds After Earl Spencer’s Claim in Diana Book
By Angel No Lie | KPD Online | 17 September 2026 | Royal Family | United Kingdom
Buckingham Palace issues rare response
Buckingham Palace has made an unusually direct response to a claim by Earl Spencer, the younger brother of the late Princess Diana, concerning an alleged conversation with the then-Prince Charles shortly after Diana’s death in 1997.
The allegation appears in Spencer’s forthcoming memoir, Swan Song: Diana, My Sister, which is due to be published on 22 September 2026. Spencer says that, during a dispute about whether Diana’s sons should walk behind their mother’s coffin, Charles told him: “Rest assured, we’ll forget her soon enough.”
Buckingham Palace did not directly confirm or deny that the conversation took place. Instead, a palace spokesperson said King Charles was mindful that “the pain of fraternal grief can cloud reason, affect judgment and colour memory” many years after a loss.
The wording represents a rare intervention by the Palace because the Royal Family generally declines to comment on claims contained in books.
A dispute over memory, not just history
At the heart of the controversy is a question that extends beyond the Royal Family: how reliable are memories formed during periods of extreme emotional distress, particularly decades later?
Spencer was Diana’s brother and was directly involved in the events surrounding her funeral. His account therefore represents the recollection of someone who was personally present during that period.
At the same time, the Palace has pointed to the potential influence of grief on recollection and judgment. Its statement does not establish that Spencer’s memory is inaccurate, but it makes clear that the King does not accept the account without qualification.
The disagreement is consequently about both what happened in 1997 and how that history should now be remembered.
Sources
The report is based primarily on current reporting from Reuters, BBC/ABC News, Sky News, The Guardian and The Independent, with the claims attributed to Earl Spencer or Buckingham Palace rather than presented as independently established facts.
General News
Eight Children Among 21 Killed After War-Damaged Gaza Building Collapses
Gaza City — 16 September 2026
Overview
At least 21 Palestinians, including eight children, were killed when a war-damaged residential building collapsed in Gaza City, according to Palestinian rescue officials and medical sources cited by international news organizations. Dozens of other people were reportedly trapped beneath the rubble as emergency crews continued searching the site on Wednesday, September 16.
The disaster occurred in an environment where large numbers of displaced Palestinians are living in buildings that were damaged during the war. The collapse has renewed concerns about the safety of structures across Gaza and the difficulties faced by rescue teams working with limited heavy equipment.
Rescue operation
Emergency crews faced major difficulties reaching people beneath the collapsed structure.
Reports from Reuters and other outlets said rescue workers lacked sufficient heavy machinery and, in some places, were forced to work with basic tools or their hands. UN personnel and Egypt’s relief agency were also reported to be assisting rescue efforts.
The shortage of equipment is particularly significant because concrete slabs from multi-storey buildings can weigh several tonnes. Attempting to remove them without cranes, excavators and cutting equipment can considerably slow the search for survivors.
Gaza’s Civil Defence has warned that many other damaged structures remain dangerous.
Reconstruction and access to equipment
The disaster has also drawn attention to the wider reconstruction crisis in Gaza.
Reuters reported that UN and Palestinian officials attributed the shortage of heavy machinery partly to restrictions affecting the entry of equipment into Gaza. Israel has said restrictions are necessary to prevent materials and equipment from being diverted to armed groups.
The result is a difficult operational environment for civil-defence teams: damaged buildings remain standing but unstable, while rescuers may lack the machinery needed both to demolish them safely and to recover people trapped inside.
The ceasefire context
The collapse comes amid a fragile ceasefire that has reduced, but not eliminated, violence in Gaza.
Reuters reported that more than 1,300 Palestinians had been killed in Gaza since the ceasefire took effect, according to Gaza health officials, while Israel reported the deaths of four soldiers during the same period. Both Israel and Hamas have accused the other of violating the ceasefire.
The building collapse demonstrates that the physical consequences of the war continue even when active fighting decreases. Structures damaged months or years earlier can remain dangerous, while displaced people continue to live among damaged infrastructure.
Key facts at a glance
| Issue | Current information |
|---|---|
| Location | Gaza City, Gaza Strip |
| Date | 16 September 2026 |
| Incident | Collapse of a war-damaged residential building |
| Reported deaths | At least 21 in AP/Independent reporting |
| Children reported killed | Reports vary; the requested figure of eight is reported by The Independent |
| Injured | At least 14 in early reports |
| Missing/trapped | Dozens; some estimates approached 100 |
| Previous building damage | Reported to have occurred during the war |
| Rescue difficulties | Severe shortage of heavy machinery and equipment |
| Wider risk | Gaza Civil Defence estimates roughly 2,000 damaged buildings may be at risk |
The casualty figures are developing and should be treated as provisional. Different news organizations and authorities have reported different numbers as rescuers continue recovering victims.
Independent assessment
The immediate facts point to two overlapping humanitarian emergencies: a deadly building collapse and a broader shortage of safe accommodation for displaced families.
The collapse itself occurred in a structure that had already been damaged during the war. The continuing use of such structures reflects the lack of sufficient safe housing and shelter options. At the same time, the limited availability of rescue equipment has complicated efforts to determine how many people remain trapped and to recover victims.
Further investigation would be required to establish the precise structural mechanism that caused the building to fail and whether additional factors contributed to its collapse.
For now, the most immediate concern remains the people still missing beneath the rubble and the safety of residents occupying other damaged structures across Gaza.
Sources: Reuters, Associated Press, The Independent, Al Jazeera and other international reporting published on 16 September 2026.
Image note: The accompanying images are illustrative rescue-scene photographs from Gaza and are not necessarily photographs of the specific building involved in this incident.
General News
U.S. Accuses Russia of Plotting Killings of Ukrainian Allies Overseas
By Angel No Lie | KPD Online | September 16, 2026
Washington, D.C. / International
Executive Summary
U.S. federal authorities have accused a network linked to Russian intelligence services of organizing a campaign of targeted killings and attacks against people regarded by Moscow as opponents, including individuals in the United States and people in European countries supporting Ukraine.
The allegations were made public on 15 September 2026, when the U.S. Department of Justice announced charges against five people it says were working with Russian intelligence services. Prosecutors allege that the network recruited people to conduct surveillance and carry out killings, while also planning attacks against civilian and military infrastructure in European countries aligned with Ukraine.
The allegations remain allegations: the five defendants are at large, and the Justice Department itself notes that an indictment is not proof of guilt and that defendants are presumed innocent unless proven guilty in court.
A second alleged target in Lithuania
The indictment describes an earlier operation involving a person in Lithuania.
U.S. prosecutors allege that in 2025, Kirill Khrameev recruited an American to travel to the Lithuanian target’s purported address and take photographs. After the surveillance was completed, Yuri Khrameev allegedly offered the individual approximately $25,000 to kill the target.
The recruit declined. Prosecutors say the alleged recruiter subsequently proposed other forms of sabotage, including attacks against property and infrastructure.
This allegation is significant because it illustrates the broader pattern described by U.S. prosecutors: the alleged network was not limited to Russian dissidents but also sought to target people and infrastructure in countries supporting Ukraine.
European dimension
The U.S. indictment also alleges that members of the network helped organize operations in Europe.
Prosecutors say Durruthy coordinated travel and logistics connected to alleged attacks in Prague in 2024 and Lithuania later that year. The Justice Department characterizes these activities as part of a wider effort involving attacks against civilian and military infrastructure in countries aligned with or perceived to be aligned with Ukraine.
The allegations come amid broader Western concerns about Russian intelligence activity in Europe.
An Associated Press investigation published in May reported that Western intelligence officials had linked a series of suspected assassination and sabotage operations to Russian security services. Those cases included alleged plots involving Ukrainian supporters, Russian activists and people connected to Ukraine’s war effort.
Why the case matters
The allegations extend beyond the traditional battlefield in Ukraine.
If the U.S. allegations are substantiated in court, they would indicate an effort to use recruited intermediaries—including people with no obvious connection to Russian intelligence—to conduct surveillance, killings and acts of sabotage abroad.
That approach can provide intelligence services with distance from the people carrying out an operation, while making investigations more difficult. The U.S. indictment alleges that recruiters offered money to individuals in the United States and Europe rather than personally carrying out every operation.
The case therefore illustrates a broader security problem facing countries supporting Ukraine: the conflict’s effects can extend beyond conventional military operations in Ukrainian territory.
Russia’s response
The allegations have been disputed by Russia.
Reuters reported on 16 September that Kremlin spokesman Dmitry Peskov dismissed the allegations pending what he described as credible evidence. Russia has previously denied involvement in killings and attempted killings of opponents abroad.
That means the central allegation—that the defendants were acting on behalf of Russian intelligence services—remains a matter to be established through evidence and legal proceedings rather than simply accepted on the basis of the charges.
What is established and what remains alleged
| Issue | Current information |
|---|---|
| Five people charged in the U.S. | Established: U.S. prosecutors unsealed charges on 15 September 2026. |
| Russian intelligence connection | U.S. allegation: prosecutors say the defendants worked for or with Russian intelligence services. |
| Planned killing in Washington | U.S. allegation: a recruit allegedly conducted surveillance and was offered $40,000 for the killing. |
| Killing actually carried out in that operation | No: the recruited U.S. resident declined to carry out the killing, according to prosecutors. |
| Earlier Lithuania operation | U.S. allegation: a recruit was allegedly offered about $25,000 to kill a target there. |
| Russian government responsibility | Contested: U.S. authorities attribute the network to Russian intelligence; Russia has rejected the allegations. |
| Criminal guilt of defendants | Not established: the defendants remain at large and are presumed innocent unless proven guilty. |
Broader context
The allegations are part of an increasingly international security environment surrounding Russia’s war against Ukraine. Western officials have previously accused Russian intelligence-linked networks of conducting sabotage, arson, surveillance and assassination operations across Europe.
In May 2026, the Associated Press reported that intelligence officials from several Western countries believed Russia had increased efforts to target opponents and supporters of Ukraine since the beginning of Russia’s full-scale invasion of Ukraine in 2022. The report also documented alleged plots in France, Lithuania, Germany and Poland.
The latest U.S. case is notable because alleged operations reached into U.S. territory itself, according to the indictment.
Conclusion
The U.S. Justice Department’s case presents an allegation of a Russian intelligence-linked network that sought to recruit people overseas to conduct surveillance, assassinations and attacks against individuals and infrastructure associated with countries supporting Ukraine.
The most immediate alleged operation involved surveillance of a Russian dissident in the United States and an offer of $40,000 for the person’s killing. Prosecutors say that operation was disrupted before the assassination occurred.
The allegations are serious but remain subject to judicial scrutiny. The five defendants have not been convicted, and Russia disputes the U.S. account. The forthcoming legal proceedings and any additional evidence will be important in determining which elements of the U.S. government’s allegations can ultimately be established.
Primary sources: U.S. Department of Justice indictment announcement; Associated Press reporting; Reuters reporting.
Image sources shown above include Wikimedia Commons and Getty Images search results; the FBI headquarters image is identified as CC BY 2.0 on Wikimedia Commons.
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